Trump's rally at an airport in Sanford, Florida, will be his first since he disclosed on October 2 that he had tested positive for COVID-19, and will kick off a three-week sprint to Election Day.
Trump, who spent three nights in a military hospital for treatment, said on Sunday that he has fully recovered and is no longer infectious, but did not say outright whether he had tested negative for the coronavirus.
Trump plans rallies in Pennsylvania, Iowa, and North Carolina later this week.
It is Biden's second campaign trip in as many weeks to Ohio, which was once thought out of reach but where polls now show a competitive race. Trump won the state by 8 percentage points four years ago and almost certainly must carry it again to win reelection.
No Republican has won the White House without carrying Ohio.