Harris will stay in Singapore for three days from Sunday, holding talks with Prime Minister Lee Hsien Loong on Monday, after which they plan to hold a joint press conference.
Also Monday, she will visit Changi Naval Base where she will board a US littoral combat ship.
She will deliver a speech the following day to underscore the importance of partnerships and areas for further cooperation, before flying to Vietnam where she will become the first sitting US vice president ever to visit the country.