The move comes after an advisory panel to the agency on Thursday did not recommend that people in high-risk jobs, such as teachers, and risky living conditions should get boosters. The panel had recommended boosters for elderly and some people with underlying medical conditions.
CDC Director Rochelle Walensky said her agency had to make recommendations based on complex, often imperfect data.
"In a pandemic, even with uncertainty, we must take actions that we anticipate will do the greatest good," she said in a statement.
The CDC recommendation follows US Food and Drug Administration authorization and clears the way for a booster rollout to begin as soon as this week for millions of people who had their second dose of the Pfizer shot at least six months ago.